THEILERIA FELIS


THEILERIA FELIS


  • EPIDEMYOLOGY-transmitted to domestic cat by tick bite.caused by cytauxzoon felis.
  • SYNONYMS-Theileria felis.
  • LOCATION-Merozoites can be found in RBC a typical parasitemias are 1% to 4% of the red blood cells. Due to the fulminant course of disease in the cat, it is more typical to observe the large schizonts in the walls of the venous system in histopathologic sections. Schizonts may also be observed in lymph node and  bone-marrow aspirates.
  • Pathogenesis-Abortion or fatal pyrexia, depression, icterus and fever may be present. Lymph node enlarged and reported in rabbit, sheep , goat,  etc. Cause abortion and still births.
  • TREATMENT: INJ buparvaquone (Butalex);drug have been shown to be successful in treating theileriosis in cattle. In the regimen employed, the disease still proved fatal. Over a 24 hour period, a cat that presented with a 2-day history of lethargy and anorexia became seriously icteric and had dark brown urine.The cat was treated with a 10 day course ofenrofloxacin followed by a 5 day course of tetracycline. Organisms were present in the cat after the ten-day course of enrofloxacin, but were not present in blood samples collected 6 and 15 weeks after discharge. It is not known why this cat survived; enrofloxacin is not known to be effective against protozoa. 
  • Most success in treatment has been achieved-diminazine aceturate (BERENIL) and imidocarb. One very ill cat responded rapidly to intravenous fluids, heparin (to treat DIC) enrofloxacin and diminizine aceturate responded well. Diminizine (2mg/kg IM) was repeated weekly for 2 more treatments. Imidocarb dipropionate (5mg/kg IM, twice, 2 weeks apart) has been found to produce a 50% cure rate

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